04 Coagulopathies

  • this lecture: coagulation cascade

  • PTT normal: 30s

  • platelet bleeding: superficial

Hemophillia

  • A for eight

  • used more often as fibrinogen restoring

Coagulation Factor Inhibitors

  • looks like hemophilia A
  • malignancy/autoimmune: antibodies develop

Vitamin K Deficiency

  • CF patients
  • neoborn: intracranial hemorrhage, increased ICP (bulging fontanelle, sunset eyes)

  • both intrinsic and extrinsic pathway
  • factor 7 shortest half life of all: first to fall, PT increases

Blood Transfusion

Liver Disease