09 Bilirubin
Bilirubin Metabolism
- 6 carbon like glucose. Very polar and soluble
- rising serum conjugated bilirubin can be detected
Hemolysis
Obstruction
- high conjugated bilirubin, also in urine
- no stercobilin
Primary Liver Disease
- fractionating into direct/indirect not helpful
- unpredictable
Rifampin/Probenecid
Gilbert
Crigler-Najjar
- babies
Dubin Johnson
- no pruritus: can excrete bile salts
Rotor
Neonatal Jaundice
Summary
