09 Gm indeterminate

  • Originally rickettsia species, now its own
  • red barn: Gram negative
  • Ram inside barn with lock: Obligate intracellular organism
  • Walnuts with poop: Contained in spore like structures in animal feces

  • Walnuts with poop: Contained in spore like structures in animal feces
  • Dust cloud: Transmitted to humans via aerosol transmission, farm animals are major reservoir

  • White, clean sheep: No rash caused
  • Q horn; Q-fever
  • coughing farmer: Pneumonia
  • hitting head: Headache
  • sweating/red face: Fever
  • Liver spot: May cause hepatitis
  • Self limiting

Mycoplasma Pneumoniae

  • Outside, no walls: "No cell wall, can't appear on gram stain"
  • cholesterol rings on goal net: Cell membrane contains cholesterol, stabilize membrane and more flexible

  • military uniform: Common in military recruits living in close quarters
  • <30: Commonly occurs in young adults

  • RBC on ground bound by IgM snow flakes: IgM cold agglutinins cause agglutination/lysis of red blood cells
  • Don't eat on ice: "Eaton's agar"
  • patchy sky: X-ray shows reticulonodular or "patchy" infiltrate, appears much worse than patients seem clinically
  • referee walking: Walking pneumonia, pt not as sick as X ray shows
  • target: Erythema multiforme. Target lesions

  • Crows: Macrolide for treatment because no cell wall

Rickettsia species

  • Inside stadium: Obligate intracellular organism
  • All white ppl: Poor gram staining. Giemsa stain for visualization
  • pink tennis balls: Weakly gram negative
  • deflated tennis balls: Coccobacillary shape
  • Coach shirt: Unable to produce CoA, gets it from eukaryotic cells
  • NAD+ bottle: Unable to produce NAD+, important for bacterial growth and reproduction, steal from eukaryotic

  • Will and Felix: Weil-Felix agglutination test for Rickettsial infections, cross reaction between rickettsia and proteus vulgaris

  • Felix sweating/touching head: Headache and fever in early Rickettsial infection
  • Rash may be associated with vasculitis
  • broken, bright red net and rackets: Vasculitis and inflammation/destruction
  • Tires: Doxycycline for treatment

Prowazekii

  • Coach with military hat: Affects military camp recruits and prisoners of war (close contact with poor hygiene
  • football shaped like louse: Spread by louse, defecates near bite spread to blood by scratching.
  • The outbreak board: Illness is called epidemic typhus (more widespread than endemic)

  • football formation: Rash starts at trunk, and spreads outward towards extremities
  • players red except helmet, hands, feet: Rash spares hands, head, and feet
  • Tackled player: Causes myalgia and arthalgia
  • coughing from dirt: Causes pneumonia
  • confused guy: Encephalitis, with and confusion. can cause coma if very serious

rickettsii

  • Rock with legs, derma center arena: Transmitted by direct bite of Dermacentor ticks (sport center)
  • Transmitted by direct bite of Dermacentor ticks

  • climber at bottom with no rash: Rash not immediate, incubation period between 2-14 days
  • 1st climber: Rash begins at extremities. Wall = source of rash
  • Rash spreads centrally from extremities
  • Climber on top grabbing head, sweating, sore from climb: Symptoms include headache, fever, myalgias