12 Exocrine Pancreas


Pancreatic Fluid

  • left side: same as plasma

  • slow flow rate: all bicarb reabsorbed
  • quick flow rate: not enough time to absorb bicarb

Pancreatic Enzymes

  • vasovagal reflex
  • signal from duodenum to pancreas via vagus nerve

  • lipase: fat

Amylase

  • active form secreted

  • breaks down into smaller saccharides

  • only monosaccharides absorbed
  • at brush border: rate limiting step

Lipase

Protein

  • auto activation of trypsin starts acute pancreatitis