13 Insulin

Rapid acting insulin

• Glulisine, aspart, lispro.
• Girls and lads

.

Regular Insulin

.

• made with bacteria

.

• same onset as rapid acting when given IV

NPH Insulin

.

• replaced often by Glargine and Detemir

Glargine

.

• often given as basal insulin once a day plus bolus rapid action
• form crystals that dissolve slowly once in body

Detemir

.

• absorb slowly once in SQ tissue
• less weight gain than Glargine

Insulin Analogs vs insulin molecules

SE

Links to this note

• step 1 Endocrinology
  • 13 Insulin

• hypoglycemia: tremor, palpitation, anxiety, seizure, coma
• weight gain: from insulin promotin FA/protein synthesis