14 Cerebellum

Anatomy

2 ways to see anatomy:

  • anterior, posterior, flocculonodular lobes
  • vermis, hermisphere

Peduncles

Inferior and middle peduncle

Superior Peduncle

  • modify motor activity of cortex

  • dentate most lateral located, influences same part of thalamus that basal ganglia influences

  • dentate most lateral, lesions behave like lateral lesions
  • other nuclei lesions behave more like medial lesions

  • purkinje can modify deep nuclei

Cerebellar Lesions

  • left side influences left body

Lateral lesions

  • dysmetria: can't control where movement happens (touch nose/finger)
  • intention tremor: begin to shake
  • leg: falling because can't position

Central

  • truncal: wobbly because can't hold trunk in midline

  • Difficult to get feet planted in right place. If too narrow will fall over, therefore wide to avoid fall

  • wide gait ataxia and falling with eyes open

  • can't coordinate movement, including mouth movement

  • nausea/vomiting due to area postrema triggered and increased ICP

Hereditary Ataxias

  • both autosomal recessive

Ataxia Telangiectasia

  • cancer usually what's fatal

Fredreich

  • remember brain, heart, pancreas