14 Ketones


  • acetone cause of fruity smell in high ketone bodies

  • liver synthesizes ketones and release them because can't use them

  • reverse of synthesis

  • FA oxidation produces NADH that drives OOA to malate

  • EtOH metabolisms makes NADH
  • high NADH depletes OAA for gluconeogenesis
  • alcoholics: hypoglycemic with ketone breath