14 Liver Disease
Tests
- enzyme in liver that transfer nitrogen groups between amino acids
- can use to see if pts drinking
- 5'-nucleotidase similar enzyme
- low
Alcoholic
- chronic leads to cirrhosis
Fatty Liver Disease
- liver enlarged in heavy drinker = fat deposition
NAFLD
Acute Hepatitis
Budd Chiari
- ascites: blood can't drain, push into portal system, out into abdomen
- hepatocellular carcinoma: liver tumor compresses cells into hepatic vein
RHF
Reye
a1 antitrypsin
- purple deposits
- glycogen also stain purple
Abscess
Hepatitis
Autoimmune
Tylenol
- right after ingestion: activated charcoal
Shock
Things cause >1000 ALT/AST:
- hepatitis
- tylenol
- shock