20 Gastric

  • erosion does not break through muscularis mucosa

Gastritis

  • acute: neutrophil
  • chronic: lymphocytes/plasma/macrophages
  • acute: acid
  • chronic: autoimmune or H. pylori

  • dyspepsia: indigestion

Acute Gastritis

  • parietal: body/fundus, not antrum

  • H. Pylori: most commonly chronic, but can cause acute

  • loss of blood flow
  • PPI to burn pts

Chronic

Pernicious Anemia

  • affects only body/fundus, where parietal cells are

Type B

  • doesn't invade mucosa, sits on top, form protective barrier

  • biopsy of lining of stomach
  • urea split into CO2

  • metaplasia, atrophy of stomach lining
  • leads to adenocarcinoma

Peptic Ulcer

  • increased acid from H. pylori

Duodenal Ulcers

  • G cells sensing alkaline env in antrum

  • pancreas just behind posterior wall

  • vomiting of coffee ground material

Gastric Ulcers

  • dangerous cause of gastric ulcer: adenocarcinoma

Treatment

Carcinoma

Intestinal

Diffuse

  • entire stomach thickened. Early satiety

  • suddenly develop keratoses

  • diffuse type of adenocarcinoma

Dyspepsia

Hypertrophic Gastropathy

  • like HCM

Menetrier

  • low protein leads to hypoalbuminemia
  • case: abd pain, edema, facial swelling, low albumin, large stomach on CT