ARDS acute respiratory distress syndrome

• related: ICU intensive care unit
• tags: #literature

---

Diagnosis

• diagnosing ARDS

Ventilator strategies

• ventilation strategies for ARDS includes low tidal volume, high peep, target plateau pressure of 30
• table for low tidal volume mechanical ventilation and PEEP FiO2
• use proning for severe hypoxemia in ARDS
• prone ventilation improves RV hemodynamics

Medical interventions

• neuromuscular blockade does not improve mortality in ARDS
• Meduri Protocol
• inhaled NO and prostacyclins showed improvement in oxygenation for ARDS without mortality benefit ¹

Follow Up

• 6 min walk test correlates to quality of life in post ARDS survivors

Literature Notes

• Proseva Prone Positioning in Severe Acute Respiratory Distress Syndrome trial
• FACTT Trial showed restrictive fluid strategy leads to mortality improvement
• DEXA ARDS showed improvement in mortality with high dose dexamethasone
• CESAR trial showed ECMO reduced mortality in ARDS

Fluid Balance

Sedation

Steroids

Severe ARDS Treatment

Neuromuscular Blockade

APRV

APRV has been shown to be comfortable to patients and may

reduce ventilator days

• Initial settings: Phigh 30, Plow 0, Thigh 5.4, Tlow 0.6.

ECMO

Links to this note

• ICU intensive care unit

  • ARDS acute respiratory distress syndrome

• use proning for severe hypoxemia in ARDS

  • related: ARDS acute respiratory distress syndrome

• FACTT Trial showed restrictive fluid strategy leads to mortality improvement

  • related: ARDS acute respiratory distress syndrome

• Proseva Prone Positioning in Severe Acute Respiratory Distress Syndrome trial

  • related: ARDS acute respiratory distress syndrome

• table for low tidal volume mechanical ventilation and PEEP FiO2

  • related: ARDS acute respiratory distress syndrome

• DEXA ARDS showed improvement in mortality with high dose dexamethasone

  • related: ARDS acute respiratory distress syndrome

• 6 min walk test correlates to quality of life in post ARDS survivors

  • related: ARDS acute respiratory distress syndrome

• diagnosing ARDS

  • related: ARDS acute respiratory distress syndrome, ICU intensive care unit

• neuromuscular blockade does not improve mortality in ARDS

  • related: ARDS acute respiratory distress syndrome

• ventilation strategies for ARDS includes low tidal volume, high peep, target plateau pressure of 30

  • related: ARDS acute respiratory distress syndrome, ICU intensive care unit

Footnotes

1. http://pulmcast.com/mind-palace/2017/3/28/87tgbtindf66y8poht0r9s3ae77w3c ↩