ARDS acute respiratory distress syndrome

• related: ICU intensive care unit
• tags: #literature

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Diagnosis

• diagnosing ARDS

Ventilator strategies

• ventilation strategies for ARDS includes low tidal volume, high peep, target plateau pressure of 30
• table for low tidal volume mechanical ventilation and PEEP FiO2
• use proning for severe hypoxemia in ARDS

Medical interventions

• Meduri Protocol
• inhaled NO and prostacyclins showed improvement in oxygenation for ARDS without mortality benefit ¹

ECMO

Literature Notes

• Proseva Prone Positioning in Severe Acute Respiratory Distress Syndrome trial
• ACURASYS trial showed cisatracurium nimbex for ARDS lowered mortality
• FACTT Trial showed restrictive fluid strategy leads to mortality improvement
• DEXA ARDS showed improvement in mortality with high dose dexamethasone
• CESAR trial showed ECMO reduced mortality in ARDS

Fluid Balance

Sedation

Steroids

Severe ARDS Treatment

Neuromuscular Blockade

APRV

APRV has been shown to be comfortable to patients and may

reduce ventilator days

• Initial settings: Phigh 30, Plow 0, Thigh 5.4, Tlow 0.6.

ECMO

Links to this note

• ICU intensive care unit
  • ARDS acute respiratory distress syndrome
• FACTT Trial showed restrictive fluid strategy leads to mortality improvement
  • related: ARDS acute respiratory distress syndrome
• Proseva Prone Positioning in Severe Acute Respiratory Distress Syndrome trial
  • related: ARDS acute respiratory distress syndrome
• table for low tidal volume mechanical ventilation and PEEP FiO2
  • related: ARDS acute respiratory distress syndrome
• DEXA ARDS showed improvement in mortality with high dose dexamethasone
  • related: ARDS acute respiratory distress syndrome
• diagnosing ARDS
  • related: ARDS acute respiratory distress syndrome, ICU intensive care unit
• use proning for severe hypoxemia in ARDS
  • related: ARDS acute respiratory distress syndrome
• ventilation strategies for ARDS includes low tidal volume, high peep, target plateau pressure of 30
  • related: ARDS acute respiratory distress syndrome, ICU intensive care unit

Footnotes

1. http://pulmcast.com/mind-palace/2017/3/28/87tgbtindf66y8poht0r9s3ae77w3c ↩