fresh frozen plasma and cryoprecipitate have no role in factor 10a reversal

Fresh frozen plasma is not helpful for reversing factor 10a inhibitors (apixaban, rivaroxaban) and contains very little factor X. Cryoprecipitate also lack factor X.1

Footnotes

  1. Tomaselli GF, Mahaffey KW, Cuker A, et al. 2017 ACC Expert Consensus Decision Pathway on management of bleeding in patients on oral anticoagulants: a report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways. J Am Coll Cardiol. 2017;70(24):3042-3067. PubMed ↩