hctz can treat nephrogenic DI via inducing proximal water reabsorption with diuresis and decreased delivery to collecting duct

• related: diabetes insipidus
• tags: #permanent
• source: uptodate

HCTZ induces mild hyponatremia, resulting in decreased water delivery to distal site and lower urine output

Links to this note

• diabetes insipidus
  • hctz can treat nephrogenic DI via inducing proximal water reabsorption with diuresis and decreased delivery to collecting duct