HCV

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• mixed cryoglobulinemia
  • Mixed cryoglobulinemia syndrome is a vasculitis due to the deposition of immune complexes (polyclonal IgG and IgM rheumatoid factor) within the vascular wall of smalland medium-size vessels. Most cases arise in those with chronic HCV virus (as is likely in this patient with a history of intravenous drug use), but patients with lymphoproliferative disorders, autoimmune disease, and other infections are also at risk.