noninvasive PAP ventilation does not prevent reintubation in ICU


Esteban trial in 2004 found for patients with respiratory failure and was intubated for at least 48 hours and then extubated, noninvasive positive pressure ventilation did not prevent reintubation compared to standard medical therapy. Rate of mortality was higher in noninvasive ventilation group.1

Footnotes

  1. Esteban A, Frutos-Vivar F, Ferguson ND, et al. Noninvasive positive-pressure ventilation for respiratory failure after extubation. N Engl J Med. 2004;350(24):2452-2460. doi:10.1056/NEJMoa032736