pleurx - tunneled catheter


Daily vs every other day drainage

  • ASAP trial: daily drainage has higher rate of pleurodesis
  • AMPLE2: no difference in breathlessness
  • or 3x a week drainage
  • also hard to tell difference if pleurodesis is from spontaneous or from chemo

  • combining TPC and talc slurry shows increased pleurodesis rate

Outpatient vs inpatient

  • no difference vs outpatient

  • combining all 3: early studies showed possible, no real data

  • AMPLE3: TPC vs surgical

  • pleuroperitoneal shunt
  • no catheter maintenance, no external device