Sweet syndrome
- related: Dermatology
- aka acute febrile neutrophilic dermatosis
- pathophysiology: after URI or GI infection, in setting of heme problems such as MDS or myelodysplastic syndrome evolving to AML
- association with medications that stimulates neutrophils: all-trans retinoic acid, GCS-F
- sx:
- high fever
- neutrophilia
- leukocytosis with left shift
- elevated inflammatory markers
- muscle/joint pain
- dense dermal infiltrate on histology
- "juicy" skin lesions: painful, edematous, red to violet
- no infection, responsive to steroids
Links to this note
- Dermatology
- rheumatoid arthritis
- neutrophilic dermatoses: Sweet syndrome or pyoderma gangrenosum
mimics cellulitis
