trastuzumab and anthracycline
- related: heart failure
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- heart failure
- Drug induced cardiomyopathy includes trastuzumab and anthracycline.
In most patients, trastuzumab-associated cardiotoxicity is reversible; there is complete recovery of cardiac function after treatment discontinuation. In contrast, chronic anthracycline-associated cardiotoxicity may not be reversible after treatment discontinuation due to myocyte necrosis, destruction, and replacement by fibrous tissue.