anticoagulation agents cascade and overview


  • Warfarin is a Vitamin K antagonist. Vitamin K is required for Factor 2, 7, 9, 10, C, S
  • DOACS are direct oral anticoagulants. They are divided into 10a inhibitors and IIa inhibitors
  • 10a inhibitors:
    • Apixaban (Eliquis)
    • Rivaroxaban (Xarelto)
  • 2a inhibitors:
    • dabigatran (Pradaxa)
    • argatroban