cocaine overdose leads to catecholamine excess
- related: toxic ingestions
- tags: #permanent
- cocaine inhibits catecholamine uptake at synaptic cleft
- symptoms are result of sympathetic stimulation: euphoria, mydriasis, tachycardia, hypertension, hallucination, anxiety, diaphoresis
- result from cocaine overdose can affect multiple organs
- neuro: lower seizure threshold, stroke
- cardiac toxicity, MI, cardiomyopathy
- lung: pneumothorax, bronchospasm
- msk: hyperthermia, rhabdo1