contrast induced nephropathy is increase of serum creatinine but does not have increased attributable risk

• related: Nephrology
• tags: #nephrology #permanent

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• absolute increase of Cr by 0.5 mg/dL or 25% in 48-72 hours following contrast
• patients usually have non-oliguric AKI
• contrast may be doesn't have increased attributable risk for AKI¹
• Incidence of dialysis and death is similar between contrast and control group in meta analysis²

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• Contrast AKI happens more often with 2 hits, contrast + one of following
  • nsaids
  • ckd
  • ace/arb
  • diabetes

Links to this note

• Nephrology
  • contrast induced nephropathy is increase of serum creatinine but does not have increased attributable risk

Footnotes

1. https://www-nejm-org.wake.idm.oclc.org/doi/10.1056/NEJMra1805256 ↩

2. McDonald JS, McDonald RJ, Comin J, Williamson EE, Katzberg RW, Murad MH, Kallmes DF. Frequency of acute kidney injury following intravenous contrast medium administration: a systematic review and meta-analysis. Radiology. 2013 Apr;267(1):119-28. doi: 10.1148/radiol.12121460. Epub 2013 Jan 14. PMID: 23319662. ↩