ICU MAP targets of 65


  • Surviving sepsis has guideline for MAP of 65.1
  • Higher MAP of 80-85 does not improve mortality but has lower RRT for patients with chronic hypertension in SEPSISPAM. Higher MAP goal increases atrial fibrillation risks. 2
    • Higher MAP could be tried in patients with cirrhosis or poor urine output.
  • 65 trial shows that MAP > 60 is safe in patients over age 65.3
  • Patients with chronic hypotension could be tried with lower MAP goal.
    • Patients with ESRD could also be tried on lower MAP goal (AKI is not a concern).
  • trauma patient may have lower MAP goal. 4

Footnotes

  1. https://pubmed.ncbi.nlm.nih.gov/28101605/

  2. https://www.nejm.org/doi/10.1056/NEJMoa1312173

  3. https://emcrit.org/pulmcrit/65trial/

  4. trauma resuscitation mtp