most common cause of bronchiectasis is postinfectious


There are many causes of bronchiectasis. However, most common cause in adult patients are post infectious followed by idiopathic. In general, it is divided into CF vs non-CF causes as management can be different.

  • immunodeficient disorders
  • chronic infections
  • genetic and hereditary disorders:
    • CF, primary ciliary dyskinesia, alpha 1 antitrypsin disease
    • Mournier-Kuhn syndrome
    • Williams Campbell
    • Ehlers Danlos
  • autoimmune:
    • ABPA
    • rheumatoid
    • sjogren
    • IBD (UC, Crohn's disease) 1
  • anatomic disease
    • obstruction from tumors, foreign bodies, stenosis
    • chronic aspiration

The prevalence of CF in white people in the United States is about 1:3,200, while the prevalence of non-CF bronchiectasis is closer to 1:300 for US male patients.2

Footnotes

  1. Bronchiectasis A Clinical Review

  2. Bronchiectasis Lecture by Jennifer Krall?