pathogenesis of chronic bronchiectasis from infection
- related: chronic bronchiectasis
- tags: #permanent #pulmonology
- infection leads to neutrophil inflammation and elevated proteases (use of brensocatib reduces exacerbation in bronchiectasis)
- inflammation leads to airway destruction aka bronchiectasis
- bronchiectasis leads to abnormal mucous clearance
- abnormal mucous clearance leads to bacterial colonization