pulmonary langerhans PLCH etiology, patient population


Pulmonary Langerhans cell histiocytosis (previously histiocytosis X or eosinophilic granuloma) is a rare form of interstitial lung disease that primarily affects young adults.

90% of affected are cigarette smokers.1

PLCH is a rare sporadic cystic lung disease of unknown etiology, seen in young adult smokers, that is characterized by the infiltration and destruction of the wall of distal bronchioles by CD1a-positive Langerhans-like cells.2

Footnotes

  1. Uworld Questionnaires

  2. SEEK Questionnaires