salicylate cause for AGMA

Salicylate toxicity most commonly presents in adults as respiratory alkalosis or with features of both respiratory alkalosis and increased anion gap metabolic acidosis.

  • symptoms: tinnitus, nausea, abd pain
  • treat with bicarb, alkalinize the blood as much as possible, the rest with rest in to urine and bind salicylates, and pee out
  • do not use acetazolamide: this doesn’t have increased serum bicarb
  • do dialysis if salicylate > 100 or having sx + 80
  • low pH < 7.2

  • pt can have normal AG but high osmolar gap in the beginning as things are metabolized over time.