sarcoidosis labs and diagnosis


Labs

  • elevated inflammatory markers: ESR
  • hypercalcemia with hypercalciuria
  • elevated ACE level can suggest sarcoidosis
  • Increased levels of vitamin D (macrophages inside the granulomas convert vitamin D to its active form.)
  • can have interstitial nephritis
  • increased gammaglobulins 1
  • Elevated alkaline phosphatase if there is liver involvement
  • Heart block: 3rd degree (most common) or 1st degree
    • look for new onset AV block in young patients 2
  • Ventricular arrhythmia: sustained or nonsustained ventricular tachycardia and ventricular premature beats

Diagnosis

Footnotes

  1. Cutaneous Manifestations of Internal Disease

  2. OPPM sarcoidosis 2