systemic heparin is used as anticoagulation in CRRT
- related: Nephrology
- tags: #permanent
- Most centers do not start with anticoagulation in CRRT.
- anticoagulation otions include regional citrate and heparin
- citrate is not approved for CRRT in US
- citrate causes less bleeding but requires change in dialysate
- decrease buffers (lactate and bicarb) since citrate is a buffer
- increase mag concentration since citrate can bind mag
- unfractionated heparin is usually used.1