TXA did not benefit CABG patients

• related: TXA tranexamic acid uses
• tags: #literature #hemeonc

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In the ATACAS trial, >4,600 patients undergoing CABG received tranexamic acid 30 min after induction. The primary outcome was a composite of death and thrombotic complications and was not different between the groups. While there was a reduction in the incidence of major hemorrhage after surgery, there was also an increase in the incidence of seizures.¹²

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• TXA tranexamic acid uses
  • TXA did not benefit CABG patients

Footnotes

1. SEEK Questionnaires ↩

2. Myles PS, Smith JA, Forbes A, et al; ATACAS Investigators of the ANZCA Clinical Trials Network. Tranexamic acid in patients undergoing coronary-artery surgery. N Engl J Med. 2017;376(2):136-148. PubMed ↩