calculations for sensitivity, specificity, PPV, NPV
- related: Biostats
- tags: #literature #boards
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A 55-year-old patient with a history of moderate COPD is admitted to the hospital with community-acquired pneumonia that leads to ARDS requiring mechanical ventilation. No organisms were identified on laboratory testing. After 7 days on the ventilator, the patient develops a new fever. Repeat cultures are sent, along with a new fungal assay by a cross-covering colleague who quotes a 90% sensitivity and 60% specificity for the new assay from a recent multicenter cohort study of 600 immunocompromised ICU patients of whom 200 were determined to have true fungal infection by a composite gold standard. Based on this information, and knowing your patient may not be as immunocompromised as those in the referenced manuscript, which of the following statements is correct?