Biostats

---

• related: Step 3, Medicine

---

MISC

• power and confidence level of research
• type 1 and 2 errors

Study Designs

• study designs
• explanatory vs pragmatic trials
• cross over study allows subjects to act as own control
• noninferiority trials
• validation methods in big data analysis

Statistic Calculations

• high sensitivity rules out, high specificity rules in
• positive predictive value
• sensitivity, specificity, PPV, NPV, true positive, false positive, true negative, false negative
• PPV has positive relationship with prevalence
• mean, median, mode
• sensitivity analysis
• comparison tests in statistics
• per year rates
• relative risk vs odds ratio
• hazard ratio vs relative risk
• coefficient of determination
• attributable risk
• likelihood ratios
• relative risk reduction
• multiplicity phenomenon
• number needed to screen and prevalence
• calculating efficacy
• calculating survival probability
• person time rate

Avoiding Bias

• bias
• intention to treat preserves randomization and prevents selection bias
• competing risk of death
  • Competing Risk of Death - An Important Consideration in Studies of Older Adults
• using prespecified subgroups is stronger study design than post-hoc subgroup
• internal vs external validity

Analysis Methods

• Kaplan Meier survival curve and Cox proportional hazards model
• funnel plot
• linear regression
• time to event analysis
• propensity matching
• receiver operating characteristics curve
• means end analysis

Links to this note

• Medicine

  • Biostats

• competing risk of death

  • related: Biostats, Competing Risk of Death - An Important Consideration in Studies of Older Adults

• Competing Risk of Death - An Important Consideration in Studies of Older Adults

  • related: Biostats, competing risk of death

• high sensitivity rules out, high specificity rules in

  • related: Biostats

• cross over study allows subjects to act as own control

  • related: Biostats

• explanatory vs pragmatic trials

  • related: Biostats

• attributable risk

  • related: Biostats

• bias

  • related: Biostats

• calculating efficacy

  • related: Biostats

• calculating survival probability

  • related: Biostats

• coefficient of determination

  • related: Biostats

• comparison tests in statistics

  • related: Biostats

• funnel plot

  • related: Biostats

• hazard ratio vs relative risk

  • related: Biostats

• intention to treat preserves randomization and prevents selection bias

  • related: Biostats

• internal vs external validity

  • related: Biostats

• likelihood ratios

  • related: Biostats

• linear regression

  • related: Biostats

• means end analysis

  • related: Biostats

• multiplicity phenomenon

  • related: Biostats

• noninferiority trials

  • related: Biostats

• number needed to screen and prevalence

  • related: Biostats

• person time rate

  • related: Biostats

• per year rates

  • related: Biostats

• positive predictive value

  • related: Biostats

• power and confidence level of research

  • related: Biostats

• PPV has positive relationship with prevalence

  • related: Biostats

• propensity matching

  • related: Biostats

• receiver operating characteristics curve

  • related: Biostats

• relative risk reduction

  • related: Biostats

• relative risk vs odds ratio

  • related: Biostats

• sensitivity, specificity, PPV, NPV, true positive, false positive, true negative, false negative

  • related: Biostats

• sensitivity analysis

  • related: Biostats

• study designs

  • related: Biostats

• time to event analysis

  • related: Biostats

• type 1 and 2 errors

  • related: Biostats

• validation methods in big data analysis

  • related: Biostats