Biostats
Study Designs
- study designs
- explanatory vs pragmatic trials
- cross over study allows subjects to act as own control
- noninferiority trials
Statistic Calculations
- high sensitivity rules out, high specificity rules in
- PPV is highest with highest specificity
- positive predictive value
- mean, median, mode
- sensitivity analysis
- comparison tests in statistics
- per year rates
- relative risk vs odds ratio
- coefficient of determination
- attributable risk
- likelihood ratios
- relative risk reduction
- multiplicity phenomenon
Avoiding Bias
- bias
- intention to treat preserves randomization and prevents selection bias
- competing risk of death
- using prespecified subgroups is stronger study design than post-hoc subgroup
- internal vs external validity
Analysis Methods
- Kaplan Meier survival curve and Cox proportional hazards model
- funnel plot
- linear regression
- time to event analysis
- propensity matching
- receiver operating characteristics curve
Links to this note
- Medicine
- competing risk of death
- Competing Risk of Death - An Important Consideration in Studies of Older Adults
- related: Biostats, competing risk of death
- high sensitivity rules out, high specificity rules in
- related: Biostats
- cross over study allows subjects to act as own control
- related: Biostats
- explanatory vs pragmatic trials
- related: Biostats
- attributable risk
- related: Biostats
- bias
- related: Biostats
- coefficient of determination
- related: Biostats
- comparison tests in statistics
- related: Biostats
- funnel plot
- related: Biostats
- intention to treat preserves randomization and prevents selection bias
- related: Biostats
- internal vs external validity
- related: Biostats
- likelihood ratios
- related: Biostats
- linear regression
- related: Biostats
- multiplicity phenomenon
- related: Biostats
- noninferiority trials
- related: Biostats
- per year rates
- related: Biostats
- positive predictive value
- related: Biostats
- PPV is highest with highest specificity
- related: Biostats
- propensity matching
- related: Biostats
- receiver operating characteristics curve
-
related: Biostats
-
- relative risk reduction
- related: Biostats
- relative risk vs odds ratio
- related: Biostats
- sensitivity analysis
- related: Biostats
- study designs
- related: Biostats
- time to event analysis
- related: Biostats