CAR-T and cytokine release syndrome
- related: Oncology
- tags: #literature #hemeonc
- host immune system activated to attack underlying cancer
- ICANS: CNS mediated inflammatory response
- most important: identify patients who need early therapy
- simple criteria: fever, hypotension, hypoxemia
- ICANS: steroid very effective
- as you suppress immune system, you make CAR-T less likely to work. Consult oncology early.1