clevidipine can cause hypoxemia via pulmonary shunting
- related: Pulmonology
- tags: #permanent
Normal physiology: hypoxic pulmonary vasoconstriciton
Cleviprex dilates pulmonary vessels and leads to decreased V/Q ratio (pulmonary shunting)
vasopressor may be better because it does not act on pulmonary vasculatures.1 In contrast, inhaled pulmonary vasodilators such as epoprostenol does not cause hypoxic pulmonary vasoconstriction.
Links to this note
- Pulmonology
- epoprostenol does not cause hypoxic pulmonary vasoconstriction
- Epoprostenol (Flolan) is inhaled pulmonary vasodilator. As opposed to systemic pulmonary vasodilator (clevidipine can cause hypoxemia via pulmonary shunting), It does not cause pulmonary vasoconstriction because the inhaled medication is only delivered to ventilated lungs and not all lungs.