CPAP improves LV afterload by preventing upper airway collapse


  • patients with OSA have occluded airway with inspiration
  • this leads to more negative intrathoracic pressure, essentially creating more vacuum
  • negative intrathoracic pressure leads to higher transmural pressure in the heart, increase LV afterload
  • CPAP keeps airway open during inspiration and decreases LV afterload.1

Footnotes

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