high sensitivity rules out, high specificity rules in
- related: Biostats and Study Design
- tags: #permanent #pulmonology
SPin, SNout
- For a high sensitive test, a negative test rules out a disease (low false negative).
- For a high sensitive test, a positive test does not rule in (high false positive).
- For a low sensitive test, a negative test does not necessarily rule out disease.
- For high specificity test, a positive test rules in (low false positive)
- For a high specificity test, a negative test does not rule out (high false negative)
- For a low specificity test, a positive test does not rule in
- sensitivity and specificity test refers to if patient with or without the disease and the likelihood of testing positive or negative. It does not refer to likelihood of a person with positive/negative test and having/not having a disease:

| Positive Test | Negative Test | |
|---|---|---|
| High sensitivity test | does not rule in | rules out |
| Low sensitivity test | - | - |
| High specificity test | rules in | does not rule out |
| Low specificity test | - | - |
Links to this note
-
use in lab sleep testing instead of home for complicated sleep apnea
- HSAT has lower sensitivity and higher specificity (high sensitivity rules out, high specificity rules in) compared to in lab testing
-
use prothrombin time to rule out dabigatran related bleeding