high sensitivity rules out, high specificity rules in

• related: Biostats
• tags: #permanent #boards

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• Biostats
  • high sensitivity rules out, high specificity rules in
• use in lab sleep testing instead of home for complicated sleep apnea
  • HSAT has lower sensitivity and higher specificity (high sensitivity rules out, high specificity rules in) compared to in lab testing
• use prothrombin time to rule out dabigatran related bleeding
  • high sensitivity rules out, high specificity rules in

SPin, SNout

• For a high sensitive test, a negative test rules out a disease (low false negative).
• For a high sensitive test, a positive test does not rule in (high false positive).
• For a low sensitive test, a negative test does not necessarily rule out disease.
• For high specificity test, a positive test rules in (low false positive)
• For a high specificity test, a negative test does not rule out (high false negative)
• For a low specificity test, a positive test does not rule in
• sensitivity and specificity test refers to if patient with or without the disease and the likelihood of testing positive or negative. It does not refer to likelihood of a person with positive/negative test and having/not having a disease:

	Positive Test	Negative Test
High sensitivity test	does not rule in	rules out
Low sensitivity test	-	-
High specificity test	rules in	does not rule out
Low specificity test	-	-