DRESS syndrome causes


Drug hypersensitivity syndrome (DHS) and drug reaction with eosinophilia and systemic symptoms (DRESS) are synonymous and represent another severe life-threatening medication reaction. The most common culprit medications include sulfonamide antibiotics, allopurinol, and anticonvulsants, but many more medications have been implicated (Table 30).12345

Footnotes

  1. SEEK Questionnaires

  2. Calle AM, Aguirre N, Ardila JC, et al. DRESS syndrome: a literature review and treatment algorithm. World Allergy Organ J. 2023;16(3):100673. PubMed

  3. Kardaun SH, Sekula P, Valeyrie-Allanore L, et al; RegiSCAR study group. Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction. Results from the prospective RegiSCAR study. Br J Dermatol. 2013;169(5):1071-1080. PubMed

  4. Wei BM, Fox LP, Kaffenberger BH, et al. Drug-induced hypersensitivity syndrome / drug reaction with eosinophilia and systemic symptoms. Part I. Epidemiology, pathogenesis, clinicopathological features, and prognosis. J Am Acad Dermatol. 2023:S0190-9622(23)02402-7. PubMed

  5. MKSAP