HALT IT trial showed TXA Did not improve mortality in GI bleed
- related: GI bleed
- tags: #permanent
- TXA tranexamic acid has uses for trauma bleed
- inhaled TXA may be helpful in nonmassive hemoptysis
- for patients with acute GI bleed, meta analysis of numerous small trials have not shown improvement in mortality from bleeding. However, TXA group had higher rate of PE and DVT. 1
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HALT-IT Trial Collaborators. Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. Lancet. 2020;395(10241):1927-1936. doi:10.1016/S0140-6736(20)30848-5 ↩