tpa contraindications


Contraindications to fibrinolysis with tPA for stroke include:

  • Presence of active internal bleeding
  • Bleeding diathesis (eg, platelets <100,000/µL)
  • Presence of intracranial hemorrhage on CT scan
  • Intracranial surgery in the last 3 months
  • Blood pressure >185/110 mm Hg

Contraindications for PE includes:

  • intracranial neoplasms
  • recent intracranial or spinal surgery or trauma
  • a history of hemorrhagic stroke
  • or a nonhemorrhagic stroke within the prior 3 months1

Footnotes

  1. SEEK Questionnaires